New Generation Sequencing

The massively parallel sequencing technology known as next-generation sequencing (NGS) has revolutionized the biological sciences.

With its ultra-high throughput, scalability, and speed, NGS enables researchers to perform a wide variety of applications and study biological systems at a level never before possible.

Illumina Technology Overview

Our technologies support a wide range of genetic analysis research applications, such as:

  • Whole-Genome Sequencing: A comprehensive method for analyzing entire genomes.
  • Genotyping: Studying variation in genetic sequences.
  • Gene Expression and Transcriptome Profiling: Analyzing which genes and transcripts are expressed in a given sample.
  • Epigenetics: Studying heritable changes in gene regulation that occur without a change in the DNA sequence.

Our Core Technologies

Next-Generation Sequencing

Sequencing with ultra-high throughput, scalability, and speed.

Sequencing by Synthesis (SBS) Technology

Learn how NGS works and what it can do for you.

A highly economical, scalable NGS technology that supports massively parallel sequencing.

BeadArray Microarray Technology

A fundamentally different approach to high-density microarrays.

Today's complex genomic research questions demand a depth of information beyond the capacity of traditional DNA sequencing technologies.

Next-generation sequencing has filled that gap and become an everyday research tool to address these questions.

See What NGS Can Do For You

What NGS Can Do For You

NGS technology has fundamentally changed the kinds of questions scientists can ask and answer.

Innovative sample preparation and data analysis options enable a broad range of applications. For example, NGS allows researchers to:

  • Rapidly sequence whole genomes
  • Zoom in to deeply sequence target regions
  • Utilize RNA sequencing (RNA-Seq) to discover novel RNA variants and splice sites, or quantify mRNAs for gene expression analysis
  • Analyze epigenetic factors such as genome-wide DNA methylation and DNA-protein interactions
  • Sequence cancer samples to study rare somatic variants, tumor subclones, and more
  • Study microbial diversity in humans or in the environment


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